MSG5000: Mass Spect Gold Human Urine, Ultra-Low Hormones & Steroids, Toxicology Negative
Introducing our Mass Spect Gold Human Urine, the definitive choice for researchers requiring a pristine testing matrix. This superior product is specially treated to achieve ultra-low levels of hormones and steroids, and screened to ensure a toxicology-negative profile for drugs of abuse.
MSG5000 is ideal for the most demanding mass spectrometry analyses in fields such as endocrine research, doping control, and toxicological studies.
Donors have been tested and found negative or non-reactive for HIV 1/2, HBsAg, HCV, HIV-1 (NAT), HCV (NAT), and RPR by FDA approved methods.
Source: Human Urine
Country of Origin: United States
Filtration: 0.2 µm
Analytes: Reference specification sheet
Storage Temp: -20°C
Definition: Defined as -15°C to -30°C
Request a quote or general inquiry for bulk pricing, COA, or specification sheet.
Introducing our Mass Spect Gold Human Urine, the definitive choice for researchers requiring a pristine testing matrix. This superior product is specially treated to achieve ultra-low levels of hormones and steroids, and screened to ensure a toxicology-negative profile for drugs of abuse.
MSG5000 is ideal for the most demanding mass spectrometry analyses in fields such as endocrine research, doping control, and toxicological studies.
Donors have been tested and found negative or non-reactive for HIV 1/2, HBsAg, HCV, HIV-1 (NAT), HCV (NAT), and RPR by FDA approved methods.
Source: Human Urine
Country of Origin: United States
Filtration: 0.2 µm
Analytes: Reference specification sheet
Storage Temp: -20°C
Definition: Defined as -15°C to -30°C
Request a quote or general inquiry for bulk pricing, COA, or specification sheet.
Introducing our Mass Spect Gold Human Urine, the definitive choice for researchers requiring a pristine testing matrix. This superior product is specially treated to achieve ultra-low levels of hormones and steroids, and screened to ensure a toxicology-negative profile for drugs of abuse.
MSG5000 is ideal for the most demanding mass spectrometry analyses in fields such as endocrine research, doping control, and toxicological studies.
Donors have been tested and found negative or non-reactive for HIV 1/2, HBsAg, HCV, HIV-1 (NAT), HCV (NAT), and RPR by FDA approved methods.
Source: Human Urine
Country of Origin: United States
Filtration: 0.2 µm
Analytes: Reference specification sheet
Storage Temp: -20°C
Definition: Defined as -15°C to -30°C
Request a quote or general inquiry for bulk pricing, COA, or specification sheet.
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The article discusses the use of a validated liquid chromatography tandem mass spectrometry (LC–MS/MS) assay to measure urine concentrations of homovanillic acid (HVA) and vanillylmandelic acid (VMA). These are end-stage metabolites of catecholamines and serve as biomarkers for neuroblastoma, a pediatric malignancy. The study demonstrated high agreement and a strong correlation between the urinary markers, making it the first large-scale application of LC–MS/MS for quantification of HVA and VMA in neuroblastoma patients in Korea.
"Mass Spect Gold Human Urine (MSG5000)" by Golden West Diagnostics was acquired to prepare the calibrators used in the study. The calibrators were made by diluting stock solutions of HVA and VMA with the MSG5000 blank urine to reach desired concentrations for the calibration curve. This was a key element in the process, as accurately prepared calibrators are crucial for ensuring the validity of the LC–MS/MS method's results.
The full paper can be accessed on PubMed Central: PMC Article Link.
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The article from NCBI focuses on a study about the role of Adenosine Deaminase (ADA) in prostate cancer (PCa) progression. It highlights that PCa is more common and aggressive in African-American men and emphasizes the disease's complexity due to its heterogeneity. The study uses metabolomics to investigate PCa's mechanisms, finding that ADA is upregulated in PCa and linked to more aggressive tumors and worse survival rates. The research suggests that increased ADA expression could promote tumor growth and spread.
The use case of MSG5000 by Golden West is mentioned in the context of measuring adenosine and inosine levels in urine for the study. MSG5000 serves as a urine matrix for preparing these measurements, which are crucial for understanding ADA's role in PCa progression.
The full text can be accessed on PubMed Central.
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The paper presents a high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method developed to accurately measure 15 urinary estrogens and estrogen metabolites (EM). These measurements are important for epidemiological studies on breast cancer etiology. The method requires only a small volume of urine and includes hydrolysis, extraction, and derivatization steps.
The article points out that a urine matrix—specifically mentioning human urine (Golden West Diagnostics)— was used to prepare calibration standards and quality-control samples for the assay. Golden West provided a urine matrix free of detectable levels of estrogens and estrogen metabolites, which served as a blank slate for establishing calibration curves and ensuring the assay's accuracy.
For the full detailed article, you may access the publication through the provided link by the American Association for Cancer Research.