SP1070: Human Serum Double Charcoal Treated and Delipidized from Defibrinated Plasma

This study examined the application of gas chromatography/mass spectrometry (GC/MS) for measuring glucose and fructose in various clinical samples.

For their analysis, the researchers used delipidized, defibrinated human serum obtained from Golden West Biologicals, catalog number SP1070-4. This SP1070 product specification implies that it was specially prepared to be free from lipids and fibrin clots, allowing for the accurate assessment of glucose and fructose in serum without interference from these substances.

The study showcased the utility of SP1070 Human Serum as a suitable matrix for enzymatic assays, providing a reliable substrate for the precise detection and quantification of these sugars in a clinical and research context.

You can find the full study and further information about the methodology and results at PubMed Central.

This study discusses the importance of early detection of cerebrotendinous xanthomatosis (CTX), a rare and treatable neurodegenerative disorder.

As part of the study, SP1070 charcoal-stripped pooled human serum provided by Golden West was used. Such a product is especially useful in diagnostic contexts where serum components could interfere with the detection of specific target molecules, such as the biomarkers for CTX.

The authors argued that including CTX in newborn screening programs could prevent its debilitating consequences through early intervention, showcasing the potential of preventive medicine in this domain. The use of SP1070 serum could support the researchers' efforts in validating their screening tests and verifying their sensitivity and specificity.

For a detailed understanding of the study's methodology, results, and implications, you can access the full article on ScienceDirect.

This study discusses how the human liver is regulated by the reproductive state, with changes in liver size and function during pregnancy and post-weaning.

To investigate these alterations, bile acid profiling was performed using plasma samples from pregnant women. Golden West’s SP1070 charcoal stripped plasma was used to prepare calibration standards, enabling the researchers to accurately quantify plasma bile acids and 7alpha-hydroxy-4-cholesten-3-one using liquid chromatography-tandem mass spectrometry (LC-MS/MS).

SP1070 served as a standardized matrix for this analysis, crucial for obtaining reliable measurements free from potential confounding factors commonly present in non-stripped plasma.

The full study can be accessed for more comprehensive details through this link: PubMed

This study aimed to compare data between an automated chemiluminescent immunoanalyzer (CLEIA) and conventional radioimmunoassays (RIA) for plasma aldosterone concentration (PAC) and plasma renin activity (PRA) in patients with primary aldosteronism (PA).

As part of the study, the Accuraseed® immunoanalyzer facilitated rapid determination of these values, while SP1070, a charcoal stripped serum prepared from human plasma by Golden West Diagnostics, was used for creating calibration standards to ensure the accurate measurement of PAC with the CLEIA kits.

The study highlighted the potential of using the rapid Accuraseed® immunoanalyzer-based measurements in clinical practice for screening and diagnosing PA, emphasizing the consistency between the new and traditional methods.

To explore the study in more detail, the full article is accessible at PLoS One.